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Ac-GRR-NH2 Inhibition of WNV Protease
| Michaelis-Menten models | Kd (μM) | Kd2 (μM) | kcat (s−1) | Ki1 (μM) | Ki2 (μM) |
|---|---|---|---|---|---|
| Substrate & mixed inhibition | 122 ± 10 | 1265 ± 174 | 0.027 ± 0.001 | 180 ± 13 | 549 ± 44 |
| Simple mixed inhibition | 60 ± 6 | - | 0.018 ± 0.0005 | 146 ± 25 | 726 ± 105 |
| Simple competitive inhibition | 51 ± 10 | - | 0.017 ± 0.001 | 59 ± 11 |
