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Ranges for interpretation of I2 following the Cochrane Handbook for Systematic Reviews of Interventions (Version 5.0.1) [23].
| 0% to 40% | might not be important |
| 30% to 60% | may represent moderate heterogeneity |
| 50% to 90% | may represent substantial heterogeneity |
| 75% to 100% | considerable heterogeneity |
