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Overexpression of HER-2/neu gene and protein in colorectal cancer
| Immunohistochemical score | n (%) | FISH amplification | n (%) |
|---|---|---|---|
| 0 | 0 (0) | > 4 signals/cell | 0 |
| 1+ | 7 (7) | > 4 signals/cell | 0 |
| 2+ | 9 (8) | > 4 signals/cell | 1 |
| 3+ | 2 (2) | > 4 signals/cell | 2 (2) |
HER-2 protein was not over expressed in non-malignant colorectal specimens. The HER-2/neu gene was not over amplified in selected non-malignant specimens.
