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Follistatin treatment does not affect SMA disease modifiers. SMN protein in p10 triceps (A and B) or upper spinal cord (C and D) lysates were examined by western blot. Both actin and IP90 are shown as loading controls. Graphs were quantified and average SMN/actin ratios are shown. Plastin-3 protein levels were also examined in p10 spinal cord lysates (E and F) by western blot, using actin as a loading control. n.s., not significant.
