TABLE 1.

Structural statistics for CTD-EF in Na_v1.5

Restraints for calculation
Total NOE restraints	2131
Intraresidue	466
Sequential	554
Medium range	526
Long range	585
Dihedral angle restraint	51
Constraint violations, mean ± S.D.
Distance violations
0.1 Å < d < 0.2 Å	1.6 ± 1.0
d > 0.2 Å	0
Average maximum distance violations (Å)	0.13 ± 0.03
Torsion angle violations >5.0°	0
Average maximum torsion angle violations	0
(degree)
AMBER energiesa, mean ± S.D. (kcal mol−1)
Restraint	1.8 ± 0.4
van der Waals	−741 ± 8
Total molecular	−4021 ± 10
Precision, root mean square deviation from the mean (Å), ordered regionsb
Backbone	0.47 ± 0.07
All heavy atoms	1.09 ± 0.10
Ramachandran statisticsc(%)
Most favored	86.8
Additionally allowed	12.6
Generously allowed	0.4
Disallowed (only for residues 1-16 and 55)	0.2

^aSee Ref. 21.

^bResidues 20-94.

^cPROCHECK nomenclature (32).