Table 3.
The risk evaluation of MDM2 SNP309 genotypes on the development of breast cancer in Taiwanese women
| SNP309a | OR (95% CI)b | p-value | OR (95% CI)c | p-value | OR (95% CI)d | p-value |
|---|---|---|---|---|---|---|
| TT | 1 | 1 | 1 | |||
| TG | 1.98 (1.00 to 3.98) | 0.05 | 2.24 (0.97 to 5.19) | 0.06 | 2.12 (0.90 to 5.00) | 0.08 |
| GG | 2.26 (0.95 to 5.38) | 0.07 | 3.40 (1.21 to 9.57) | 0.02 | 3.05 (1.04 to 8.95) | 0.04 |
| TG+GG | 2.06 (1.05 to 4.06) | 0.04 | 2.48 (1.10 to 5.60) | 0.03 | 2.30 (1.00 to 5.30) | 0.05 |
a The frequency of each genotype is referred to Table 2.
b The crude OR values.
c Age-adjusted OR values.
d These OR values are the results adjusted for age, BMI, cardiovascular disease/diabetes, and OCP (Oral Contraceptive Pill) usage