TABLE 4.

Pathology results of explanted hearts

1	2	3	4	5	6	7	8	9
RV: focal endocardial hemorrhage LV: patchy contraction band necrosis and coagulative necrosis, with moderate interstitial edema but no significant interstitial hemorrhage	RV: edema, with very minute foci of contraction band necrosis (midwall) LV: contraction band necrosis in both the inferior wall and inferior septum extending from midwall to subendocardium, with interstitial edema	RV: minute areas of early necrosis in subendocardium, with some contraction band necrosis LV: similar scattered areas of recent ischemic necrosis most pronounced in interventricular septum	Extensive coagulative necrosis and dystrophic calcification of subendocardial myocytes extending to the endocardial surface of both ventricles, consistent with peritransplant reperfusion ischemic injury/infarction	LV: very large LV infarct with reperfusion changes Note: Thromboemboli in pulmonary artery, with large right upper lobe infarct	Hyperacute rejection with interstitial hemorrhage	RV: recent (24 h to 48 h) extensive subendocardial RV infarct; no pre-existing donor heart disease, with widely patent coronary arteries and no evidence of rejection LV: relatively spared, with very recent subendocardial infarct (mild and patchy) Note: Changes of pre-existing pulmonary hypertension were noted	Mild to moderate rejection	Accelerated acute rejection in the first heart transplant

LV Left ventricle; RV Right ventricle