Table 2.
Metabolite concentrations (pmol/well, mean ± SD) measured in hepatocytes after BDE-99 exposure.
| Donor
|
|||
|---|---|---|---|
| Metabolite | 1 (n = 6) | 2 (n = 4) | 3 (n = 4) |
| 2,4,5-Tribromophenola | 9.31 ± 1.6 | 96.3 ± 2.3 | 8.36 ± 0.24 |
| 5′-OH-BDE-99 | 20.8 ± 2.5 | 302.9 ± 41.4 | 11.2 ± 0.2 |
| Penta-OH-BDE | 23.3 ± 2.6 | 155.6 ± 12.2 | 13.6 ± 0.7 |
| Tetra metabolite 1b | NQ | 18.7 ± 1.1 | NQ |
NQ, not quantified; n, number of replicates/wells.
a
Estimated using response of 2,4,6-tribromophenol.
b
Estimated assuming GC/MS response of tetra-OH-BDEs.