Figure 3.

MA plots of differential expression and signal intensity measurements using the multispecies endocrine microarray for control and exposed fish (loess normalization). (A–D) Individual LACSD-exposed fish versus pooled controls. (E–G) Individual OCSD-exposed fish versus pooled controls. (H) Pooled controls versus pooled controls. (I–K) Individual control fish versus pooled control. Each point represents data from a single 65mer oligonucleotide probe. M is a measure of differential gene expression [log₂ (exposed /control)] in A–G or absence of significant differential gene expression in the self–self plots [log₂ (control/control intensity)] in H–K. A is a measure of signal intensity [(0.5 log₂ exposed intensity + 0.5 log₂ control intensity) in A–G or (0.5 log₂ control intensity + 0.5 log₂ control intensity) in H–K].