Skip to main content
. 2009 Mar-Apr;16(2):203–210. doi: 10.1197/jamia.M2805

Table 1.

Table 1 List of the Drugs Included in the Study

Drug Class Molecules Recommended Adjustments
Antibiotics Vancomycin LD+ SC
Teicoplanin, Gentamicin, Amikacin, Tobramycin, LD+ I+SC
Ciprofloxacin, Levofloxacin, Norfloxacin, LD+ I+SC
Erythromycin, Fosfomycin D
Sulfamethoxazole-Timethropim I
ACEI Ramipril, Perindropril, Captopril, Lisinopril D
B-adrenergic blocking agents Acebutolol, Bisoprolol, Sotalol D
Atenolol D+ 1
Antigout drugs Colchicine, Allopurinol D
Digoxin Digoxin, hemigoxin LD+ D+1
Antidiabetes drugs Metformin† D

An alert was triggered if the estimated glomerular filtration rate (eGFR) of the patient was <60 mL/min/m2: the recommendations could relate to the loading dose (LD), the maintenance dose (D), the interval (I), and the need to further adjustment according to the serum concentration (SC).

The metformin alert was triggered if eGFR < 80 mL/min/m2 and medication was contraindicated for eGFR < 30 mL/min/m2.

ACEI = angiotensin converting enzyme inhibitor.