Table 1.
Table 1 List of the Drugs Included in the Study †
Drug Class | Molecules | Recommended Adjustments ∗ |
---|---|---|
Antibiotics | Vancomycin | LD+ SC |
Teicoplanin, Gentamicin, Amikacin, Tobramycin, | LD+ I+SC | |
Ciprofloxacin, Levofloxacin, Norfloxacin, | LD+ I+SC | |
Erythromycin, Fosfomycin | D | |
Sulfamethoxazole-Timethropim | I | |
ACEI | Ramipril, Perindropril, Captopril, Lisinopril | D |
B-adrenergic blocking agents | Acebutolol, Bisoprolol, Sotalol | D |
Atenolol | D+ 1 | |
Antigout drugs | Colchicine, Allopurinol | D |
Digoxin | Digoxin, hemigoxin | LD+ D+1 |
Antidiabetes drugs | Metformin† | D |
∗ An alert was triggered if the estimated glomerular filtration rate (eGFR) of the patient was <60 mL/min/m2: the recommendations could relate to the loading dose (LD), the maintenance dose (D), the interval (I), and the need to further adjustment according to the serum concentration (SC).
† The metformin alert was triggered if eGFR < 80 mL/min/m2 and medication was contraindicated for eGFR < 30 mL/min/m2.
ACEI = angiotensin converting enzyme inhibitor.