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. 2009 Mar-Apr;16(2):203–210. doi: 10.1197/jamia.M2805

Table 4.

Table 4 Type of Recommendation and Drug Category of Prescriptions Included in Control and Intervention Periods

Type of Recommendation Control Periods Intervention Periods p Value
Total 587 535
Need for measuring eGFR 64 103
Need for dosage adjustment 523 432
First prescriptions 406 301
Following prescriptions 117 131
Drug category† ‡ 0.05
ACEI 136 (26.0) 147 (34.0)
B-adrenergic blocking agent 136 (26.0) 117 (27.1)
Antibiotic 141 (27.0) 87 (20.1)
Antigout drug 63 (12.0) 41 (9.5)
Digoxin 36 (6.9) 30 (7.0)
Antidiabetes drug 11 (2.1) 10 (2.3)

Chi-square test comparing drug categories in intervention and control periods.

Drug category (medications included): ACEI (ramipril, perindropril, captopril, lisinopril); B-adrenergic blocking agents (acebutolol, atenolol, bisoprolol, sotalol); antibiotics (ciprofloxacin, erythromycin, gentamicin, vancomycin, levofloxacin, sulfamethoxazole-timethropim, amikacin, teicoplanin, tobramycin, norfloxacin, and fosfomycin); antigout drug (colchicine, allopurinol); digoxin; antidiabetes drug (metformin).

Values are expressed as number (percentage of total prescriptions needing dosage adjustment).

ACEI = angiotensin-converting enzyme inhibitor; eGFR = estimated glomerular filtration rate.