Table 4.
Table 4 Type of Recommendation and Drug Category of Prescriptions Included in Control and Intervention Periods
Type of Recommendation | Control Periods | Intervention Periods | p Value ∗ |
---|---|---|---|
Total | 587 | 535 | |
Need for measuring eGFR | 64 | 103 | |
Need for dosage adjustment | 523 | 432 | |
First prescriptions | 406 | 301 | |
Following prescriptions | 117 | 131 | |
Drug category† ‡ | 0.05 | ||
ACEI | 136 (26.0) | 147 (34.0) | |
B-adrenergic blocking agent | 136 (26.0) | 117 (27.1) | |
Antibiotic | 141 (27.0) | 87 (20.1) | |
Antigout drug | 63 (12.0) | 41 (9.5) | |
Digoxin | 36 (6.9) | 30 (7.0) | |
Antidiabetes drug | 11 (2.1) | 10 (2.3) |
∗ Chi-square test comparing drug categories in intervention and control periods.
† Drug category (medications included): ACEI (ramipril, perindropril, captopril, lisinopril); B-adrenergic blocking agents (acebutolol, atenolol, bisoprolol, sotalol); antibiotics (ciprofloxacin, erythromycin, gentamicin, vancomycin, levofloxacin, sulfamethoxazole-timethropim, amikacin, teicoplanin, tobramycin, norfloxacin, and fosfomycin); antigout drug (colchicine, allopurinol); digoxin; antidiabetes drug (metformin).
‡ Values are expressed as number (percentage of total prescriptions needing dosage adjustment).
ACEI = angiotensin-converting enzyme inhibitor; eGFR = estimated glomerular filtration rate.