Table 3.
Biochemical and Hormonal parameters between ApoE haplotypes in patient group
| Haplotypes and parameters (Mean ± SD) | ||||
|---|---|---|---|---|
| E2 | E3 | E4 | P value | |
| Total-cholesterol (mg/dl) | 188.20 ± 40.13 | 200.36 ± 39.43 | 207.40 ± 30.45 | 0.503 |
| LDL- cholesterol (mg/dl) | 111.20 ± 29.32 | 118.12 ± 29.82 | 121.00 ± 25.76 | 0.712 |
| HDL- cholesterol (mg/dl) | 59.00 ± 16.18 | 55.66 ± 12.37 | 66.00 ± 22.68 | 0.067 |
| Triglycerides (mg/dl) | 110.50 ± 45.34 | 125.00 ± 54.90 | 106.90 ± 69.22 | 0.468 |
| Fasting Glucose (mg/dl) | 92.70 ± 6.91 | 91.03 ± 7.32 | 94.30 ± 10.37 | 0.360 |
| Basal Insulin (mIU/ml) | 11,20 ± 7..61 | 12.18 ± 9.56 | 13.10 ± 5.32 | 0.893 |
| Homocysteine(µmol/L) | 2.73 ± 1.62 | 2.57 ± 1.61 | 3.13 ± 1.49 | 0.569 |
| FSH (mIU/ml) | 5.48 ± 1.80 | 5.54 ± 1.74 | 4.19 ± 1.80 | 0.069 |
| LH (mIU/ml) | 8.50 ± 5.16 | 6.29 ± 3.33 | 6.98 ± 5.00 | *0.018 |
| Estradiol (pg/ml) | 38.20 ± 20.70 | 33.53 ± 19.79 | 46.00 ± 29.43 | 0.167 |
| DHEA-S (µg/dl) | 247.11 ± 127.18 | 222.39 ± 86.19 | 240.30 ± 78.69 | 0.597 |
| 17-OHP (ng/ml) | 1.98 ± 1.25 | 1.74 ± 0.85 | 1.29 ± 0.51 | 0.177 |
| Total-Testosterone (ng/ml) | 0.86 ± 0.29 | 1.04 ± 1.48 | 0.63 ± 0.20 | 0.503 |
| Free-Testosterone (pg/ml) | 3.30 ± 1.53 | 3.48 ± 1.84 | 2.61 ± 1.52 | 0.343 |
| Prolactine(pmol) | 18.36 ± 10.55 | 17.33 ± 7.09 | 13.00 ± 3.09 | *0.046 |
| Fibrinogen (mg/dl) | 343.81 ± 72.34 | 369.50 ± 74.70 | 365.70 ± 85.13 | 0.560 |
*P < 0.05 values were accepted as statistically significant