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. 2008 Feb 12;580(3-3):291–297. doi: 10.1016/j.ejphar.2007.11.014

Fig. 4.

Fig. 4

5-HT docked into a homology of the 5-HT3 receptor (Reeves et al., 2003). A. The extracellular domains of two subunits of the 5-HT3 receptor showing the location of the binding pocket (boxed) at their interface. B. Enlarged image of the binding site showing the proximity of the hydroxyl group of 5-HT to the hydrophilic residues Asn128, Glu129 Thr179, Thr181 and Glu236.