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. Author manuscript; available in PMC: 2009 Aug 15.
Published in final edited form as: J Immunol. 2009 Feb 15;182(4):2340–2348. doi: 10.4049/jimmunol.0802767

Figure 5.

Figure 5

Mesenteric Lymph Node (MLN) cells from S isolate infected mice treated with anti-CD25 secrete a reduced level of the IL-10 and levels of the Th2 cytokines. S isolate infected C57BL/6 mice were treated with 1mg anti-CD25 (mAB) or PBS weekly from d-7 excluding d0. At day 21 p.i MLN cells from naïve, PBS control and anti-CD25 treated S isolate infected mice were isolated and cultured with parasite specific ES antigen for 48hrs. A. Levels of IFN-γ, IL-12p70, IL-10, IL-6, IL-4, IL-5, IL-9 and IL-13 in MLN supernatants were measured by CBA; all cytokine data are pg/ml (A). Values represent the mean ± SD for five mice per group. *, significant difference between the PBS control and anti-CD25 S isolate infected mice (Mann Whitney U * = p<0.05, **=p<0.01)

B. Worm numbers in mice from both PBS control and anti-CD25 treated groups were counted at days 21 and 28p.i. (B) Each symbol represents an individual animal and the line represents the mean with 5 mice per group. Experiments were performed at least twice and data shown is a representative experiment.