Table 1. ETC activity in SH-SY5Y cells following 12 days of PINK1 silencing.

siRNA	ETC Activity
	I	II+III	IV
PINK1 #1	14.2±4.1	5.4±1.2	0.068±0.012*
PINK1 #2	13.6±2.6	4.8±0.8	0.059±0.011*
control	20.1±6.4	7.5±1.9	0.132±0.024

SH-SY5Y cells were transfected with PINK1 or scrambled control siRNA for 12 days and the activities of complexes I, II+III and IV were measured. Data are expressed against citrate synthase activity and multiplied by 100. Data are the mean±s.e.m (n = 5) * P<0.05 vs. control siRNA.