Figure 2. Extracellular (1–3) and early membrane (4–7) reactions involved in pheromone perireception and reception events.

1: Pheromone uptake from air (L_air) to sensillar lymph (L) and transport through sensillar lymph by PBP. 2: Deactivation (enzyme N) producing deactivated pheromone P. 3: Interaction with receptor R. 4: Activation of receptor (R*). 5: G-protein activation (G*). 6: Effector enzyme activation (E*). 7: Production of second-messengers (DAG and IP₃). In the present work, all these reactions were modeled as previously described [36].