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. 2009 Mar 20;5(3):e1000321. doi: 10.1371/journal.pcbi.1000321

Figure 5. Plots of dose-conductance functions.

Figure 5

Illustrate eqs. (2) and (3) for (A) the DAG-gated cationic conductance G cat and (B) the Ca2+-gated Cl conductance G Cl. The solid blue lines in A and B represent the conductance without inhibition. The EC50 of the cationic current, K mcat = 0.01 µM of DAG, is reached at U = 10−4.25 µM/s, i.e. this current is most active at low pheromone uptakes. The EC50 of the cationic current, K mCl = 81 µM of Ca2+ corresponding to U = 50 µM/s, i.e. the Cl current is most active at high uptakes. The dashed red lines represent the conductance at half-maximum inhibition (intermediate curve) and maximum inhibition (rightmost curve) by CaCaM (A) and PKC* (B). The PKC* inhibition of the Cl current is very weak and practically negligible.