Table 5. Fitted parameters (28) of ionic channels.

Channel	Parameter	Symbol	Value	Unit	Sensitivity1	log10 U 2	Characteristic3
IP3-gated Ca2+ channel	Maximal conductance	G MCa	0.14	nS	−1.45	−4.75	R
	EC50 for IP3	K mCa	3.48	µM	−4.71×10−2	−3.5	R
	Hill coefficient for IP3	n Ca	1	–	−0.43	0.25	F
	Maximal inhibition	i MCa	3.08	–	−2.22×10−2	1.5	F
	IC50 for CaCaM	K iCa	0.61	µM	7.85×10−2	−0.25	F
	Hill coef. for CaCaM	n iCa	2.51	–	−8.53×10−3	−1.75	F
DAG-gated cationic channel	Maximal conductance	G Mcat	1.23	nS	1.03	0.25	F
	EC50 for DAG	K mcat	0.0104	µM	−93.9	0	F
	Hill coefficient for DAG	n cat	0.86	–	−2.99	0	F
	Maximal inhibition	i Mcat	53.2	–	−1.83×10−2	0	F
	IC50 for CaCaM	K icat	0.0377	µM	7.65	−4.75	H
	Hill coef. for CaCaM	n icat	0.818	–	−0.84	−4.25	R
Ca2+-gated Cl− channel	Eq. potential Cl−	E Cl	−11.5	mV	6.08×10−2	1.5	F
	Maximal conductance	G MCl	16.8	nS	5.54×10−2	1.5	F
	EC50 for Ca2+	K mCl	81.2	µM	−1.10×10−2	0.75	F
	Hill coefficient for Ca2+	n Cl	1.52	–	−1.30	−2.75	H
	Maximal inhibition	i MCl	1.4	–	2.51×10−2	1.5	F
	IC50 for PKC*	K iCl	0.06	µM	−0.24	−4.5	R
	Hill coef. for PKC*	n iCl	1.1	–	2.64×10−2	0.75	F
Ca2+ extrusion	Equilibrium potential	E x	−17.1	mV	−0.12	1.5	F
	Maximal conductance	G Mx	2.21×10−3	nS	−658	−0.25	F
	EC50 for Ca2+	K mx	0.54	µM	0.62	−3.75	R
	Hill coefficient for Ca2+	n x	0.605	–	1.30	−4.75	R
Ca2+- and voltage-gated K+ channel	Maximal conductance	G MK	4.88	nS	3.40×10−2	−4.0	R
	EC50 for Ca2+	K mK	2.83×10−4	µM	−676	−4.75	F
	Coef. of voltage depend.	A K	12.5	mV	2.20×10−2	−4.75	F
Conversion factors Ca2+	For IP3-gated channel	f Ca	4.87	µM pC−1	3.56×10−2	−4.75	R
	For DAG-gated channel	f cat	2.50	µM pC−1	0.50	0.5	F

^{1, 2, 3}Same presentation as in Table 4.