Figure 5.

Rates of evolution of the six mitochondrial and cytosolic carbonic anhydrase isozymes of human and mouse. Rates are from the phylogenetic tree in Fig. 5. Column 1 shows the average of the human and mouse branches since the human and mouse ancestor (HMA) for each of the six isozymes. Columns 2–6 show percent sites replaced (after Poisson correction for undetected multiple hits) on internal branches of the tree from each duplication (1, 2a, 2b, 3a, 3b) until the human–mouse ancestor for the relevant isozymes. Column 6 shows the corrected percent sites replaced (average of human and mouse) from the earliest duplication (3b) until present for each of the six isozymes.