Figure 2.

Phylogeny of vertebrate anx4 proteins. (A) Identity and similarity comparisons between structural domains of the anxa4 proteins. Percentage identities are in regular type and similarities are in italics. Annexin fold domains are represented by shaded boxes and the N- and C-terminal and inter-fold domains are represented by horizontal lines, using anx4a as the reference sequence. (B) Molecular phylogenetic tree of Xenopus orthologs and vertebrate anxa4 proteins. The unrooted tree was produced for all the available anxa4 proteins (see Table 1 for Accession numbers) using the PHYLIP program on the Genebee Internet Site.