Table 5.
Adjusted odds ratios (ORs) and corresponding 95% confidence intervals for the risk of Barrett's esophagus in relation to cigarette smoking status, smoking cessation, and total pack-year of tobacco use (cases vs. GERD comparison)
| # BE/GERD | Cases vs. GERD controls OR (95%CI) | |
|---|---|---|
| Smoking status* | ||
|
| ||
| Non-smoker | 108/129 | 1 (ref) |
| Ever smoker | 212/187 | 1.21 (0.87-1.70) |
|
| ||
| Current smoker | 51/40 | 1.27 (0.80-2.02) |
| All former smokers | 161/147 | 1.21 (0.85-1.73) |
|
| ||
| # Years since smoking cessation** | ||
|
| ||
| Less than 5years | 19/14 | 3.79 (0.93-15.4) |
| 5-14.9 | 36/33 | 3.42 (1.24-9.43) |
| 15-24.9 | 38/39 | 0.87 (0.41-1.87) |
| 25+ | 38/31 | 0.97 (0.54-1.74) |
| Per year since quit smoking | 0.99 (0.96-1.01) | |
| p-value for trend | 0.24 | |
|
| ||
| # Packyears* | ||
|
| ||
| Non-smoker | 108/129 | 1 (ref) |
| <10 | 52/48 | 1.26 (0.79-2.04) |
| 10-30 | 65/57 | 1.24 (0.79-1.95) |
| 30-50 | 48/30 | 1.68 (0.97-2.92) |
| 50+ | 47/49 | 0.95 (0.55-1.62) |
| Per pack-year | 1.00 (0.99-1.00) | |
| p-value for trend | 0.813 | |
*
The model was controlled for age, race (white vs. non-white), gender, and education
**
The model was controlled for all the above mentioned variables plus pack-year of smoking.