. Author manuscript; available in PMC: 2009 Mar 2.

Published in final edited form as: J Allergy Clin Immunol. 2009 Jan;123(1):146–152.e8. doi: 10.1016/j.jaci.2008.10.047

TABLE E8.

Results of backward linear regression of selected clinical features on the percentage of glutathione disulfide (GSSG) in the ELF^*

Model	Regression coefficient	SE	t	P value	95% CI
Included variables^†
Constant	76.604	10.850	7.060	<.001	(53.603, 99.604)
Sex	−27.726	12.254	−2.263	.038	(−53.703, −1.749)
Airway eosinophils (%)³	−16.469	6.957	−2.367	.031	(−31.218, −1.720)
Excluded variables
Ethnicity	0.114		0.491	.631
Prednisone dose (mg)	0.064		0.234	.818
Age (y)	−0.017		−0.061	.952
Airway neutrophils (%)^‡	−0.169		−0.717	.484
ICS dose	0.355		1.515	.151

Data are from the combined sample of subjects with severe asthma with and without airway obstruction, excluding adult and pediatric controls.

^†

Sum of squares (model/total) =4170.2/12,966.1; R² = 0.322; P = .045.

^‡

Data were logarithmically transformed for analysis.