. Author manuscript; available in PMC: 2009 Mar 2.

Published in final edited form as: J Allergy Clin Immunol. 2009 Jan;123(1):146–152.e8. doi: 10.1016/j.jaci.2008.10.047

TABLE E4.

Biomarkers of oxidant stress in children with asthma excluded from data analysis

	Severe asthma AO− included in data analysis (n = 30)	Severe asthma AO+ included in data analysis (n = 25)	Severe asthma excluded from data analysis (n = 9)
GSH (μmol/L)	94 ± 107	57 ± 95	34 ± 51^*
GSSG (μmol/L)	39 ± 61	72 ± 76	16 ± 15^†
GSH + GSSG (μmol/L)	134 ± 150	129 ± 134	50 ± 48
% GSSG	36 ± 27	62 ± 24	55 ± 38^*
E_h GSH:GSSG (mV)	−119 ± 44	−96 ± 30	−82 ± 45^*
H₂O₂ (μmol/L)	12 ± 13	15 ± 18	31 ± 46
MDA (μmol/L)	38 ± 12	51 ± 39	95 ± 93
8-Isoprostanes (μmol/L)	405 ± 274	1073 ± 1929	827 ± 1228

Data are expressed per mL of epithelial lining fluid (ELF) and represent the mean ± SD. Differences between groups were analyzed with non-parametric Mann-Whitney U statistics. Post-hoc testing was performed on significant variables with ANOVA and Tukey tests.

P < .05 vs severe asthma AO−.

^†

P < .05 vs severe asthma AO+.