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. Author manuscript; available in PMC: 2009 Mar 2.
Published in final edited form as: Transfusion. 2008 Mar;48(1 Suppl):39S–46S. doi: 10.1111/j.1537-2995.2007.01575.x

TABLE 1.

Conduit and coagulation parameters in aprotinin versus control group

Assay Aprotinin group (n = 54) Control group (n = 201) p Value
Endothelium
 % CD31 staining* 51.2 ± 16.9 49.5 ± 19.7 NS
Coagulation
 TEG-MA (mm)† 71.1 ± 5.1 70.4 ± 3.7 NS
 WBA—5 μg collagen† 11 ± 4 12 ± 3 NS
 Fibrinogen (mg/dL)† 693 ± 104 643 ± 132 NS
 D-dimer (ng/mL)† 1643 ± 226 1769 ± 197 NS
 Perioperative change in F1.2 (%)* 60 ± 44 116 ± 91 0.04
Flow
 Mean flow* 38 ± 31 40 ± 39 NS
 Pulsatility index* 2.5 ± 0.6 2.8 ± 0.5 NS
 Percent diastolic flow* 54 ± 14 58 ± 18 NS
*

Perioperative changes in F1.2, SVG endothelial integrity, and blood flow were assessed intraoperatively.

†

Coagulation tests were compared at their peak levels on Postoperative Day 3.

TEG-MA = thromboelastography PLT mapping; WBA = whole-blood aggregometry.