Table 1.
Clinical characteristics of lung cancer patients with BRAF mutations. A total of 916 NSCLC patient samples were analyzed, and 17 mutations in BRAF were identified. Percentages were calculated as a function of the total number of BRAF cases (17), and as a function of the total number of cases analyzed (916).
| BRAF mutant (n=17)
|
Total (n=916)
|
|||
|---|---|---|---|---|
| n | % | % | ||
| BRAF mutation | Total | 17 | (100%) | 1.9 % |
| Exon 11 | 4 | (24%) | 0.4 % | |
| Exon 15 (non-V600) | 2 | (12%) | 0.2 % | |
| Exon 15 (V600E) | 11 | (65%) | 1.2 % | |
| Wild type | - | 98.1% | ||
|
| ||||
| Gender | Male | 6 | (35%) | 37 % |
| Female | 11 | (65%) | 63 % | |
|
| ||||
| Histology | Adenocarcinoma | 15 | (88%) | 68 % |
| Other | 2 | (12%) | 32 % | |
|
| ||||
| Smoker2,3 | Former/Current4 | 12 | (71%) | 67% |
| Never | 5 | (29%) | 33% | |
| Median Pack-years | 50 | 415 | ||