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. Author manuscript; available in PMC: 2010 Feb 15.
Published in final edited form as: Neuroimage. 2008 Oct 29;44(4):1334–1344. doi: 10.1016/j.neuroimage.2008.10.020

Table 3.

Effects of DVR with Experimental Variables

t-test Multiple Regression with DVR:
Sex Age Weight Ketamine timing* Isoflurane timing* Injected fallypride Free fally AUCc
Mean (SD) F - 23 M - 10 4.09 yrs (± 0.60) 5.82 kg (± 1.08) 33 min (± 9) 27 min (± 9) 0.31g/kg (± 0.21) 53pmol/mL·min (± 35)
DVR p-value p-values
putamen 21.8 ± 4.4
19.0 ± 4.2
0.26 0.22 0.41 0.57 0.53 0.98 0.65
caudate-head 17.5 ± 4.2
14.8 ± 4.8
0.32 0.04 0.39 0.52 0.46 0.85 0.58
v. stri. 12.4 ± 2.1
11.4 ± 2.0
0.36 0.27 0.41 0.26 0.31 0.31 0.31
pituitary 3.03 ± 0.86
1.89 ± 0.23
0.003 0.07 0.37 0.16 0.16 0.53 0.18
amygdala 2.67 ± 0.42
2.35 ± 0.38
0.07 0.02 0.41 0.56 0.45 0.14 0.18
S.N. 2.55 ± 0.33
2.33 ± 0.38
0.15 0.08 0.57 0.05 0.05 0.05 0.03
thalamus 2.13 ± 0.39
2.13 ± 0.47
0.92 0.42 0.75 0.01 0.01 0.001 0.0004
ant. cing. 1.76 ± 0.24
1.68 ± 0.21
0.52 0.21 0.42 0.63 0.51 0.57 0.47
frontal 1.49 ± 0.28
1.24 ± 0.13
0.30 0.72 0.09 0.61 0.50 0.11 0.027
temporal 1.46 ± 0.29
1.31 ± 0.23
0.26 0.18 0.09 0.70 0.95 0.26 0.06

bold – significant when corrected for multiple comparisons

*

Ketamine (and Isoflurane) timing is the time period between ketamine (isoflurane) administration and the injection of radioligand.