Figure 2. FGF2 HMW protein expression in Fgf2^{hmw-ko/hmw-ko} mice.

(A), a representative western blot of heart (A) showing the complete absence of FGF2 HMW isoforms (21 kD & 20.5 kD) in Fgf2^{hmw-ko/hmw-ko}, FGF2 LMW isoform (18 kD) in Fgf2^{lmw-ko/lmw-ko} and both HMW (21 kD & 20.5 kD) and LMW (18 kD) isoforms of FGF2 in Fgf2−/− hearts mice. Representative western blots also indicate complete absence of FGF2 HMW (21 kD & 20.5 kD) in liver (B) and brain (C) tissues of Fgf2^{hmw-ko/hmw-ko} mice. The blots are representative of at least 3 wild-type/mutant mice pairs.