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. Author manuscript; available in PMC: 2009 Sep 15.
Published in final edited form as: J Immunol. 2008 Sep 15;181(6):3841–3849. doi: 10.4049/jimmunol.181.6.3841

Figure 6. High dose IL-1β is capable of inducing NO production in primary astrocytes.

Figure 6

TNF-α WT and KO astrocytes were seeded in 96-well plates at 1 × 105 cells per well and incubated overnight. The following day, cells were treated with the indicated concentrations of IL-1β for 24 h, whereupon nitrite levels were determined. Significant differences between unstimulated and IL-1β-treated WT astrocytes are denoted with asterisks (**, p < 0.001), whereas alterations between TNF-α WT versus KO astrocytes are indicated by hatched signs (##, p < 0.001). Results are representative of two independent experiments.