Table 1.
Candidate ICU clinical best practices considered for study
| Best Practice |
| Prophylaxis against venous thromboembolism |
| Prevention of ventilator-associated pneumonia |
| Intensive insulin therapy to achieve tight glycemic control |
| Lung protective ventilation strategy |
| Daily interruption of sedation infusions |
| Restrictive transfusion strategy |
| Prophylaxis against gastric stress ulcers |
| Spontaneous breathing trials for mechanically-ventilated patients |
| Protocolized weaning from mechanical ventilation |
| Prevention of decubitus pressure ulcers |
| Provision of early enteral nutrition |
| Prevention of catheter-related blood stream infections |
| Pain assessment and management |
| Anxiety and delirium management |
| Improved end of life care |