Table 1.

The association of studied features with prognosis (univariate survival analysis in the entire cohort)

Feature	P value (Log Rank Test)
Phospho-p38 expression (<15 vs ≥15)*	0.443
Cytoplasmic caspase-8 expression (weak vs moderate/strong)	0.037
Nuclear caspase-8 expression (<10 vs ≥10)	0.257
Bcl-2 expression (<45 vs ≥45)*	0.218
Grade (grade 1/2 vs grade 3/4)	0.019
pT-stage (stage pT1a/pT1b/pT2 vs pT3a/pT3b)	0.712
Age (<54 vs ≥54)*	0.273
Gender (male vs female)	0.660

The association of studied features with prognosis was studied with the Log Rank Test. As shown in the table, grade and cytoplasmic caspase-8 expression are both prognosticators, and of these, Fuhrman's grade is more significant. Numbers in bold: statistically significant.

(*): median values.