Table 8.
Utility of POC and OTC urine hCG testing devises to detect hCG variants. of β-core fragment by urine POC pregnancy devices.
| Device | Regular hCG | Hyperglycosylated hCG | hCG Free β | Hyperglycosylated hCG free β | β-subunit core fragment |
| A. Point of care devices | |||||
| Beckman Icon 25 | + | ? | - | - | - |
| Beckman Icon 20 | + | ? | - | - | - |
| Beckman Icon II | + | ? | - | - | - |
| Inverness Acceava | + | ? | ? | ? | - |
| Inverness Clearview | + | ? | ? | ? | - |
| Mainline Confirms | + | ? | - | - | - |
| Quidel Quick Vue | + | ? | - | - | - |
| Quidel Instant Vue | + | ? | - | - | - |
| B > Over the counter devices | |||||
| Clear Blue Easy | + | ? | + | ? | - |
| Clear Blue Easy Digital | + | ? | + | ? | - |
| E.P.T. | + | ? | + | ? | - |
| E.P.T. Digital | + | ? | + | ? | - |
| First Response | + | - | + | + | - |
| First Response Digital | + | - | + | + | - |
Devices were tested with a sample containing 2.5 μg/L (100 IU/L) pure β-core fragment and no other form of hCG. Antigens appropriately recognized by assays (detection of standard varies from calibrated concentration by no more than 25%) are indicated by +. Those invariably detected in a specific assay (result more than 50% different from calibrated concentration) are indicated by ?, and those not detected at all are indicted by -.