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. Author manuscript; available in PMC: 2010 Apr 1.
Published in final edited form as: Proteins. 2009 Apr;75(1):217–230. doi: 10.1002/prot.22236

Table VI.

Amino acid differences in the E helix and CD turn of bovine, trout IV and perch Hb. Amino acid (AA) changes are listed in the table for both the α and βs of each Hb. The known effects in oxidation (kox) and hemin loss (k−H) rates in sperm whale Mb and human Hb are listed. The appropriate references are cited.

Residue
position		 Bovine
α/β
AAs		 Trout IV
α/β AAs		 Perch
α/β AAs		 Known effect in Myoglobin or
Hemoglobin		 Reference
E10 K/K T/T T/T 1.9 × decrease in kox with T67R
Mb		 14
E11 V/V I/V I/I 15 × increase in kox with V68I
Mb		 14
CD4 F/F W/F W/F 1.8 × increase in kox and 2.6 ×
increase in k−H with F46W Mb		 39,44
CD3 H/S H/T H/N 10 × decrease in k−H, for β Ser(CD3)His mutation in HbA 55
E14 A/S N/G G/G Not documented ---