. Author manuscript; available in PMC: 2010 Mar 15.

Published in final edited form as: Dev Biol. 2008 Dec 11;327(2):280–287. doi: 10.1016/j.ydbio.2008.11.038

Table 3.

FYN (−/−) mice ovulate oocytes with meiotic progression defects

Strain	# Donors	# Oocytes	%GVBD	%MII	% abnormal MII
B6/129	5	111	100	99^a	4^c
Fyn KO	4	68	100	85^b	19^c

All ovulated oocytes initiated GVBD. A significant percentage of ovulated FYN (−/−) oocytes failed to reach metaphase-II and were blocked at metaphase-I (a,b) P<0.05. There was a tendency for FYN (−/−) oocytes to exhibit abnormal spindle and chromatin alignment however this difference was not statistically significant (c) P>0.05.