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. Author manuscript; available in PMC: 2010 Mar 1.
Published in final edited form as: J Urol. 2009 Jan 20;181(3):1467–1473. doi: 10.1016/j.juro.2008.11.008

FIGURE 1.

FIGURE 1

Representative traces of intravescial pressures and EUS-electromyogram. EUS activity during lower abdominal wall compression for 10 seconds (bar) was recorded three times at 2 minute intervals before (control) and 10 min after i.v. administration of test drugs. Abdominal compression induced increases in EUS-electromyogram activity, and cumulative application of medetomidine (Med; 0.03, 0.3 and 3 mg/kg) dose-dependently decreased the EUS activity during abdominal compression. In addition, after-discharges of EUS-electromyogram were often observed following cessation of abdominal compression, most obviously after the first compression. EUS activity was completely eliminated by α-bungarotoxin (0.4 mg/kg) at the end of experiment (lowest trace).