Table 1. Suppressor mutations identified from the prkaca-L173A background.
Suppressor | Changes in Suppressors |
Suppressor 27 | T153S, L160N, S212N |
Suppressor 28 | T153S, L160N, S212N |
Suppressor 31 | Q181K, T278S |
Suppressor 51 | M58V, R190C |
Suppressor 52 | M58V, R190C |
Suppressor 53 | M58V, R190C |
Suppressor 54 | M58V, R190C |
Suppressor 55 | Wild-type reversion |
Suppressor 57 | M58V, R190C |
Suppressor 58 | K28N, I305L, E311V, I315L |
Suppressor 59 | K28N, I305L, E311V |
Suppressor 60 | K28N, E311V |
Suppressor 61 | K21Q, K28N, R308K, E311V |
Suppressor 62 | Wild-type reversion |
Suppressor 63 | R190C, R194H, K292Q, I303V |