Table 3. Genotype counts and allele frequencies for rs8034191 by case-control status and smoking status in the Bergen discovery cohort.
Population | Smoking Status/Amount | Genotype | MAF (C) | ||
TT | CT | CC | |||
case | All | 326 | 375 | 122 | 0.376 |
ctrl | All | 391 | 328 | 91 | 0.315 |
case | Current Smoker | 139 | 186 | 58 | 0.394 |
case | Current Non-smoker | 186 | 188 | 64 | 0.361 |
ctrl | Current Smoker | 177 | 135 | 30 | 0.285 |
ctrl | Current Non-smoker | 213 | 193 | 61 | 0.337 |
case | Heavy Smoker Note 1 | 221 | 251 | 85 | 0.378 |
case | Light Smoker | 105 | 124 | 37 | 0.372 |
ctrl | Heavy Smoker | 128 | 115 | 34 | 0.330 |
ctrl | Light Smoker | 263 | 213 | 57 | 0.307 |
case | Heavy Smoker Note 2 | 233 | 247 | 79 | 0.362 |
case | Light Smoker | 92 | 127 | 43 | 0.406 |
ctrl | Heavy Smoker | 122 | 105 | 28 | 0.316 |
ctrl | Light Smoker | 268 | 223 | 63 | 0.315 |
Norwegian population controls | Population sample | 246 | 251 | 54 | 0.326 |
Note 1: Heavy smoker defined by pack-years of smoking (grouped by log transformed median = 3.11).
Note 2: Heavy smoker defined by length of smoking history (grouped by median = 41.5 yr).