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Three positions of the L1 stalk, corresponding to 3 functional states of the ribosomal E site. (A) Open state of the L1 stalk with vacant E site; (B) half-closed state of the L1 stalk with deacylated tRNA in the classical E/E state; (C) fully closed state of the L1 stalk with tRNA in the hybrid P/E state. The deacylated tRNA is shown in red; the position of the half-closed E/E state is shown by a dashed green outline.
