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. 2009 Feb 5;106(8):2617–2622. doi: 10.1073/pnas.0808270106

Fig. 1.

Fig. 1.

Architecture of human ARNT. (A) ARNT domain architecture, indicating the approximate boundaries of the nuclear localization sequence (NLS), bHLH domains, PAS domains (PAS-A, PAS-B), and transcriptional activation domains (TAD) as identified by hidden Markov model analysis (48). (B) Ribbon diagram of the solution structure of ARNT PAS-B domain (15). The side-chain positions of several residues discussed in the text are shown in stick representation. Secondary structure elements are labeled by using the nomenclature established by Gong et al. (49).