Table 2.

Summary of the statistics for the NRG1 SNPs association

NRG1 SNPs	Alleles		Phase	N		MAFs		P	OR (95%CI)
	Associated	Other		Cases	Controls	Cases	Controls
rs16879552	G	A
			500K	181	343	0.5331	0.3921	1.23 × 10−5	1.82 (1.39,2.39)
			Replication	190	507	0.4974	0.3925	4.00 × 10−4	1.55 (1.22,1.98)
			Combined	371	850	0.5148	0.3924	1.80 × 10−8	1.68 (1.40,2.00)
rs7835688	C	G
			500K	179	343	0.2682	0.1356	4.95 × 10−7	2.31 (1.67,3.21)
			Replication	191	510	0.2330	0.1529	3.85 × 10−4	1.73 (1.28,2.35)
			Combined	370	853	0.25	0.1460	1.12 × 10−9	1.98 (1.59,2.47)

N, Number of individuals successfully genotyped; MAF, Minor allele frequency; CI, confidence interval; P values and odd ratios (OR) represented in this table were obtained from fitting an additive model using logistic regression; genotyping rates for rs16879552 were 100% for HSCR patients and 99.13% for controls, and for rs7835688 were 98.90% for HSCR patients and 99.13% for controls.