Fig. 1.

Mlh heterozygosity accelerates lymphomagenesis in the absence of pfp. Kaplan-Meier curve showing percentage survival of Mlh^+/− pfp^+/+ (n = 30, gray solid line) and Mlh^+/− pfp^−/− (n = 28, black solid line) mice. Historical control representing lymphoma development in pfp^−/− mice (n = 26, black dashed line) is overlaid. Mice were monitored for at least 800 days. Asterisk represents statistically significant difference between Mlh^+/− pfp^+/+ and Mlh^+/− pfp^−/− groups (P < 0.0001, log-rank test).