Fig. 3.

Loss of pfp accelerates plasmacytoma development in v-Abl⁺ transgenic mice. Kaplan-Meier curve showing percentage survival of v-Abl⁺ pfp^+/+ (n = 41, gray solid line) and v-Abl⁺ pfp^−/− (n = 20, black solid line) mice. Historical control representing lymphoma development in pfp^−/− mice (n = 26, black dashed line) is overlaid. Mice were monitored for at least 750 days. Asterisk represents statistically significant difference between v-Abl⁺ pfp^+/+ and v-Abl⁺ pfp^−/− groups (P = 0.0003, log-rank test).