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. 2009 Feb 2;106(8):2927–2932. doi: 10.1073/pnas.0809650106

Fig. 2.

Fig. 2.

Learning increased the survival of new cells in the hippocampus. (A) Learning during trace conditioning increased the number of new cells that survived after training (* indicates that the effect of training on cell number was significant: P < 0.05). The number of BrdU-labeled cells in the dentate gyrus (GCL/SGZ and hilus) of male and female animals that learned (n = 14) is shown in contrast to the number of new cells remaining in animals that were not trained (n = 17). (B) The number of BrdU-labeled cells that were present in an animal after training correlated positively and significantly with the period during training when the animal learned to emit the CR during the trace interval. The asymptotic trial was used to estimate the trial when an animal's conditioned response rate was 95% or more of its asymptote. The asymptotic trial did not differ between male and female animals that learned (P > 0.05).