Fig. 2.

Proliferation and apoptosis in prostate samples from BPH patients. Index of proliferation was calculated by using the markers Ki67 and PCNA. (B and D) Shown is the lack of expression of proliferation in the stromal compartment. In the epithelium of some ducts, Ki67-positive (A) or PCNA-positive (C) were detected mostly in the basal layer. The antiapoptotic protein Bcl-2 was strongly detected in epithelium (E) and in some infiltrations of immune cells in the stroma (F). (Scale bar, 100 μm.)