Table 3. Genotype frequency of eNOS polymorphisms by primary outcome vasospasm and secondary outcome cerebral infarct.
| All | No Vasospasm | Vasospasm | p-value | No Infarct | Infarct | p-value | |
|---|---|---|---|---|---|---|---|
| n(%) | n(%) | n(%) | n(%) | n(%) | |||
| eNOS -786T>C | 0.15 | 0.74 | |||||
| TT | 167(53) | 91(54) | 76(50) | 77(53) | 41(56) | ||
| CT | 119(37) | 64(38) | 55(36) | 53(37) | 23(32) | ||
| CC | 33(10) | 12(8) | 21(14) | 15(10) | 9(12) | ||
| TOTALS | 319 | 167 | 152 | 145 | 73 | ||
| eNOS 894G>T (E298D) | 0.60 | 0.25 | |||||
| GG | 141(60) | 77(57) | 64(63) | 84(59) | 44(60) | ||
| GT | 63(27) | 39(29) | 24(24) | 43(30) | 16(22) | ||
| TT | 32(13) | 19(14) | 13(13) | 16(11) | 13(18) | ||
| TOTAL | 236 | 135 | 101 | 143 | 73 | ||
| eNOS VNTR* | 0.87 | 0.65 | |||||
| bb | 184(75) | 107(76) | 77(74) | 114(77) | 55(71) | ||
| ab | 53(22) | 29(20) | 24(23) | 29(20) | 19(25) | ||
| aa | 8(3) | 5(4) | 3(3) | 5(3) | 3(4) | ||
| TOTAL | 245 | 141 | 104 | 148 | 77 | ||
*
a=4 allele, b=5 or 6 allele, as 6 is very rare occurring in only 6 cases