Table 4. Parameter estimates from fitting the mother-daughter gamma distributions to the cell reproduction data for YJW512 [PSI +] [PIN +] and YJW679 [PSI +] [pin −] and their [psi −] derivatives grown in YEPD+3 mM guanidine hydrochloride.
Phenotype | λM | λD | β | θ | q | |
YJW512 | ||||||
[ PSI +] | Estimate (SE) | 1.42 (0.045) | 0.75 (0.097) | 12.04 (1.917) | 0.40 (0.013) | |
[ pin −] | Estimate (SE) | 1.44 (0.045) | 0.73 (0.101) | 13.04 (2.158) | 0.40 (0.013) | |
Combined | Estimate (SE) | 1.43 (0.032) | 0.74 (0.069) | 12.50 (1.399) | 0.40 (0.010) | 0.52 |
YJW679 | ||||||
[ PSI +] | Estimate (SE) | 1.28 (0.032) | 0.60 (0.074) | 21.33 (3.438) | 0.45 (0.012) | |
[ pin −] | Estimate (SE) | 1.31 (0.003) | 0.42 (0.007) | 23.25 (0.132) | 0.46 (0.018) | |
Combined | Estimate (SE) | 1.29 (0.022) | 0.51 (0.021) | 21.68 (2.678) | 0.46 (0.015) | 0.40 |
Footnote: Shown are parameter estimates from fitting the mother-daughter gamma distributions to the data. SE is the standard error, for θ this is a bootstrap standard error [23], with bootstrap sample size 10,000. The derivation of the growth rate or Malthusian parameter,θ, is explained in the text. q = λD/λM, and is only given for values used in conjunction with curing experiments, as described in the text.