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. 2009 Mar 9;4(3):e4736. doi: 10.1371/journal.pone.0004736

Figure 8. Peritoneal CD5+ B cell population is absent in TRAF6-ΔB mice.

Figure 8

(a) Total peritoneal exudate cells (PECs) numbers from control and TRAF6-ΔB mice. (control; n = 5, TRAF6-ΔB; n = 5) *: p<0.05 (b) Peritoneal exudate cells (PECs) from control and TRAF6-ΔB mice analyzed by flow cytometry. Total CD19+ B cells (top panels) are subdivided into B-1 and B-2 subsets (middle panels), and the CD23−CD11b+ B-1 subset is further divided into B-1a and B-1b (bottom panels). Results are representative of at least 8 mice. (c) The ratios of each B cell subset in the PECs from control, CD40 KO and TRAF6-ΔB mice are shown. Data are presented as mean±SD. (control; n = 12, CD40 KO; n = 4, TRAF6-ΔB; n = 8) *: p<0.01 compare to control. (d) Profiles of CD5 expression in B-1 cells from CD40-deficient mice and MyD88/TRIF-doubly deficient mice are analyzed as described in (b).