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. Author manuscript; available in PMC: 2009 Oct 1.
Published in final edited form as: Bioconjug Chem. 2008 Sep 20;19(10):2049–2059. doi: 10.1021/bc8002919

Scheme 1.

Scheme 1

Synthesis of the pyridyl-activated Gd(III) Chelators a

aConditions: (a) AETP, HATU, DIPEA, DMF ; (b) TFA/H2O/TIS, followed by MTBE precipitation. (c) AETP, DMSO, and H2O.