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. Author manuscript; available in PMC: 2009 Oct 1.
Published in final edited form as: Bioconjug Chem. 2008 Sep 20;19(10):2049–2059. doi: 10.1021/bc8002919

Table 1.

Relaxometric Properties of Complexes 1–4 at pH 7.4 and 37 °C

Relaxivity (mM−1s−1)a q τm (ns)c
60 MHz (1.5 T) 600 MHz (14.1 T)b
(Gd(III)-DOTA-Arg8) 1 6.8 3.50 1.0 916
(Gd(III)-DTPA-Arg8) 2 7.8 3.45 1.2 1105
(Gd(III)-DOTA-SS-Arg8) 3 6.9 3.52 0.9 840
(Gd(III)-DTPA-SS-Arg8) 4 7.4 3.46 1.1 1327
Gd(III)-DOTA 3.2 2.12 1.2d 243e
Gd(III)-DTPA 3.8 2.09 1.2d 303e
a

Measured in 100 mM phosphate buffer

b

measured at ambient temperature (~ 25 °C)

c

calculated at 25 °C

d

data from ref (51)

e

data from ref (52).