Table 1.
Body Weight (grams) | BAC mg/dl) | ||||||||
---|---|---|---|---|---|---|---|---|---|
Dose | PD4 | PD5 | PD6 | PD7 | PD8 | PD9 | Session 1 M, PD30) | Session 1 F, PD30) | PD4 |
UD | 11.1 ± 0.4 | N/A | N/A | N/A | N/A | 20.1 ± 0.8 | 93.1 ± 4.6 | 92.1 ± 1.8 | N/A |
SI | 11.2 ± 0.2 | 12.8 ± 0.2 | 14.5 ± 0.3 | 16.2 ± 0.3 | 17.8 ± 0.3 | 19.6 ± 0.4 | 100.3 ± 2.5 | 90.3 ± 2.4 | N/A |
3 g | 10.8 ± 0.2 | 12.7 ± 0.3 | 14.6 ± 0.3 | 16.6 ± 0.3 | 18.9 ± 0.3 | 21.1 ± 0.4 | 102.4 ± 2.7 | 87.6 ± 2.3 | 139.9 ± 8.6 |
4 g | 10.9 ± 0.2 | 12.2 ± 0.3 | 14.0 ± 0.3 | 15.8 ± 0.4 | 18.0 ± 0.4 | 20.3 ± 0.5 | 98.0 ± 2.8 | 87.1 ± 3.4 | 237.3 ± 17.5 |
5 g | 11.4 ± 0.2 | 11.8 ± 0.2 | 13.2 ± 0.3 | 14.6 ± 0.3 | 16.3 ± 0.4 | 18.1 ± 0.5 | 96.5 ± 3.0 | 88.3 ± 2.9 | 301.8 ± 29.1 |
UD: Undisturbed Controls; SI: Sham-intubated Controls; 3 g: 3 g/kg/day of alcohol over postnatal days (PD) 4–9; 4 g: 4 g/kg/day of alcohol over PD4-9; 5 g: 5 g/kg/day of alcohol over PD4-9