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. Author manuscript; available in PMC: 2009 Jul 15.
Published in final edited form as: Transplantation. 2008 Jul 15;86(1):46–53. doi: 10.1097/TP.0b013e31817c79c0

Figure 1. Sirolimus increases insulin secretion in impure HIP.

Figure 1

HIP were divided into two groups based on the islet purity: pure group (90–95% purity, A) and impure group (40–60%purity, B). HIP were cultured with or without 30ng/ml sirolimus for 72 hours. Glucose stimulated insulin release was examined using dynamic stimulation assay. A and B showed dynamic insulin secretion at 3 and 11 mM glucose. The data shown represent three independent experiments.